Treating ADHD is more about neurotransmitter balance than simply giving a trial of meds. These 4 neurotransmitters all contribute to ADHD improvement - PEA is the least understood.
Emerging research also implicates the neurotransmitter glutamate in the development of ADHD, likely due to its interaction with dopamine and norepinephrine.
ADHD Treatment Targets Need Clarification - Reality Changes - If you wonder why you can't get the meds right. If you wonder about diagnosis and the question: "Is it hyperactive, inattentive or combined?" - 'Context' becomes exceedingly important.