So many psych drugs appear to manifest a roving Therapeutic Window, an unpredictable metabolic pattern that appears to move around and require changing over time - thus resulting in tachyphylaxis.
The longer we deeply explore treatment disappointments [that occur everyday], the more we see significant confusion and missed diagnosis with psych med failures secondary to overlooking IgG, the "chronic antibody."
Many thousands of individuals are treated everyday for ADHD disorders using stimulant meds that don't last 24 hr, but only last for a portion of the day. So why aren't we paying attention to those important details-
For ADHD diagnosis: You can be sophisticated and smart, but if you don't know how to get where you want to go, you simply can't get there - no matter how smart you are.