Pyrrole disorder is one you must absolutely consider in treatment resistant depression: Severe pyrrole levels have been observed in persons diagnosed with violent behaviors, depression, schizophrenia, and other serious mental disorders.
Watch For: Top of the Therapeutic Window -This comment on Vyvanse is worth your time, and is so commonly seen in the office. Vyvanse in the PM is so forgiving - that when it finishes, it is hard to assess. Measure the DOE anyway - start with that process.
A little-known mental disorder marked by episodes of unwarranted anger [-sounds like ADD/ADHD at first glance] is more common than previously thought...